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This research investigates how budding yeast cells adapt to the loss of Ctf4 , a protein critical for coordinating DNA replication. The study identifies specific evolutionary pathways—including mutations in the cohesion, replication, and checkpoint modules—that allow cells to restore fitness despite constitutional DNA replication stress .

If you are looking for structural biology data, EMD-51963 refers to a Cryo-EM structure of a human GABAAcap G cap A cap B cap A sub cap A receptor complex . 51963.rar

If you tell me the or field of study (e.g., evolutionary biology, structural biology, or cybersecurity), I can confirm if this is the correct paper. This research investigates how budding yeast cells adapt