While there is currently no cure, management focuses on controlling inflammation and restoring barrier function. Atopy - StatPearls - NCBI Bookshelf - NIH
: Often the first sign in infancy, caused by skin barrier defects (e.g., filaggrin mutations) that allow for epicutaneous allergen sensitization. While there is currently no cure, management focuses
: Antigen-presenting cells perceive allergens (like pollen or dust mites) as danger signals, activating TH2 or ILC2 cells. While there is currently no cure
: These cells produce cytokines (IL-4, IL-13) that trigger B cells to differentiate into plasma cells producing allergen-specific IgE. caused by skin barrier defects (e.g.