Clonal Hematopoiesis (CH) is characterized by age-related expansion of blood cells bearing somatic mutations in genes such as DNMT3A, TET2, and ASXL1, which increases risk for cardiovascular disease and hematologic malignancies. Advanced analysis utilizes the boostDM-CH model to identify high-confidence clonal expansion drivers. For further details, consult the study available at PMC .

Causes and consequences of clonal hematopoiesis - ScienceDirect

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