B cell subsets and certain antibodies like IgG1 show significant fluctuations based on the time of year.
Studies using high-dimensional flow cytometry and single-cell sequencing show that "healthy" ranges are broader than traditionally thought: Determining the expected variability of immune ...
Heritability plays a more pronounced role in T cell populations compared to B cells , which are more susceptible to environmental cues. Specific genetic variants (ccQTLs) have been identified that regulate leukocyte counts and contribute to disease susceptibility. Expected Variation in Healthy Adults B cell subsets and certain antibodies like IgG1
The human "immunotype" is shaped by a complex interplay of heritable and non-heritable factors: Determining the expected variability of immune ...
The most potent intrinsic driver, causing a shift from precursor-biased (naïve) status to an inflammation-biased status.