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For players on Windows 10 or 11, the following adjustments are highly recommended to stabilize the game:
Try running the game in Windowed Mode or use a "Borderless Window" tool if the game crashes when Alt-Tabbing or during cinematic-to-dialogue transitions. Known Game Glitches Left dialogue crashes - Deus Ex: Human Revolution Deus ex human revolution dialogue crash fix
Change Anti-Aliasing from MSAA to FXAA ; some users report MSAA causing freezes during intro meetings. For players on Windows 10 or 11, the
Modern CPUs with many cores can cause the game to fail immediately or during heavy processing tasks. Set your default playback device to
Set your default playback device to . Graphic & Display Adjustments
Alternatively, use Process Lasso to restrict the game to fewer cores (e.g., 4 or 8) to prevent engine overflows.
If the game crashes on launch or during scene transitions, try unticking DirectX 11 in the game's launcher settings.