: Malcolm tries to prevent Dewey from being placed in the high-stress Krelboyne class, but Dewey's plan to fail the IQ test backfires, landing him in a class for emotionally disturbed students.
: The family discovers their neighbors have been throwing a celebratory party every year specifically because the Wilkerson family is away on vacation. Malcolm in The Middle - Season 5
: Malcolm continues to assert himself in high school, dealing with censorship in the school newsletter and navigating complex social circles, such as "dating" a girl's entire intellectual family. : Malcolm tries to prevent Dewey from being
: Following his birth at the end of Season 4, Jamie becomes a central figure, leading to new dynamics like "baby gambling" among local fathers and Lois struggling to maintain her usual level of control. : Following his birth at the end of
: Reese attempts to live on his own in an apartment and eventually makes a massive life change by enlisting in the Army during the season finale.