Mary undergoes intense mental torture. By the end of the episode, her brainwashing is seemingly complete when she is ordered to kill a fellow hunter and friend.

Crowley’s attempt to keep Lucifer under his control fails. Lucifer manages to reverse the security system in his vessel, overpowering Crowley and escaping his confinement.

The British Men of Letters use a "bug" (a tracking/listening device) to locate and eliminate American hunters. Sam and Dean eventually find the bug in the Impala.