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: The classification reaffirms the 9-pathway model for melanoma, which classifies lesions based on sun exposure (UV damage), anatomical site (e.g., acral, mucosal), and specific molecular drivers.

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: The MPATH-Dx V2.0 schema is proposed to help clinicians and pathologists communicate risk levels more effectively across four distinct classes. 2. Keratinocytic / Epidermal Tumours

: A dedicated new section covers epithelial tumours derived specifically from the nail bed.

: The term "variant" is now reserved strictly for genetic alterations in DNA sequences, rather than being used to describe morphological subtypes.

: Updates focus on high-risk subtypes. Sarcomatoid differentiation is now the primary acknowledged uncommon subtype of Squamous Cell Carcinoma (SCC).

Detailed information and purchasing options for the full volume are available through the IARC Publications or Amazon .

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WHO Classification of Skin Tumours